Atrial septal defect coexistent with sjogren's syndrome

Pulmonary hypertension is frequently associated with atrial septal defect and various connective tissue disorders. This case describes a 74-year-old woman who presented with symptoms of heart failure and concomitant involvement of salivary glands and keratoconjunctivitis. An echocardiogram demonstrated ostium secundum atrial septal defect with left to right shunt and severe pulmonary hypertension. Laboratory investigations confirmed the diagnosis of Sj?gren's syndrome [SS] with positive anti-nuclear factor and centromere SS-A/Ro pattern. Anti-Ro [SS-A] was found positive. Atrial septal defect was closed through transcatheter route with significant improvement in clinical outcome. This case report suggests a possible association of atrial septal defect with primary Sjogren's syndrome in an adult patient

Changing trends in hypertrophic pyloric stenosis

A three year study on Hypertrophic Pyloric Stenosis, [HPS] was conducted at the Department of Paediatric Surgery, Nishtar Hospital, Multan. Many features of HPS in published literature were not found in our study. There was male predominance, male of female ratio was 9:1. It was seen more frequently among babies of multigravida and 90% had gestation period of more than 35 weeks. Vomiting started within first week of life in all the infants. Weight of 50% patients was within normal limits. There were no gross associated anomalies, though preoperative malrotation was found in only 7.14% patients. Moderate to severe dehydration was noticed in 21.42% and hypokalaemia in 10.7% patients. Ultrasonography was diagnostic in 29.6% cases

Bacteriological studies in osteomyelitis at Faisalabad

Investigations were carried out to study the organisms associated with 80 cases of osteomyelitis at Faisalabad. Seventy eight had infection with single organism; whereas there was no growth in 2 cases. On culture, the frequency of the organisms was Staphylococcus aureus in 30 [37.5%], Streptococcus pyogenes in 28 [35%]; Escherichia coli in 16 [20%]; Salmonella in 3 [3.7%] and Proteus vulgaris in 1 [1.3%] case